A PROCEDURE FOR THE DETERMINATION OF 4-AMINOSALICYLIC ACID (p-AMINOSALICYLIC ACID) IN BLOOD AND IN URINE

Para-Aminosalicylic Acid: Pas

Synthesis and evaluation of a prodrug of 5-aminosalicylic acid for the treatment of ulcerative colitis

Objective(s): This study is aimed to design and synthesize a prodrug of 5-aminosalicylic acid and evaluate its ameliorative effect on experimental ulcerative colitis (UC).Materials and Methods: 5-Aminosalicylic acid-alanine (5-ASA-ALA) was synthesized and characterized. Its stability study was conducted in rat plasma and in the gastroint...

Failure of P-(di-n-propylsulfamyl)-benzoic acid (benemid) to influence p-aminosalicylic acid blood levels.

DEVELOPMENT OF A METHOD FOR THE DETERMINATION OF 4-HYDROXY-3-METHOXYMANDELIC ACID (VANILLYLMANDELIC ACID) IN URINE BY PAPER CHROMATOGRAPHY

We have developed a simple and precise paper chromatographic method for the determination of 4-hydroxy-3-methoxymandelic acid (VMA) in urine. Concentrations of VMA in patients with neuroblastoma were increased in comparison to controls. The linearity was excellent in the concentration range tested. The within-assay coefficient of variation for control and patient urine was less than 2.2%. ...

The differential determination of mixtures of p-aminosalicylic acid and sulphetrone or sulphonamides in body fluids.